Impact of Hereditary Angioedema on Patients
A diagnosis of hereditary angioedema (HAE) is often delayed.1
HAE diagnostic delays and misdiagnoses
A 2010 paper reported that patients saw an average of 4 different physicians before getting a diagnosis of HAE2
A 2017 survey of 445 patients with HAE had an average delay in getting an accurate diagnosis of 8.4 years (SD: 10.6 years)3
Know the signs of hereditary angioedema to help reduce the misdiagnosis of this unpredictable disease.
Impact of HAE
The burden of HAE is multifaceted. HAE not only impacts a patient's body, but also their psychological, social, and somatic functioning.1,2
- Patients with HAE may develop increased anxiety and depression associated with the unpredictability, frequency, and severity of HAE attacks3
- Patients with HAE may experience impairment of daily activities (work, education, and social)3
- There may be economic costs3
According to a 2017 self-reported survey of 445 patients with HAE3:
Approximately 9.2% of patients visited the emergency department or an urgent care facility for a mean of 5.2 visits over the past year3
Approximately 13% of patients visited a hospital and stayed an average of 1 week (7.4 nights)3
Approximately 14% of patients required intubation following a laryngeal attack3
The study was conducted by physicians and scientists from Massachusetts General Hospital, Research Triangle Park, and Takeda.3
Manage HAE with a treatment plan which includes on-demand for every patient and consideration of long-term prophylactic medications to help prevent HAE attacks.4
